[原著論文] (下線は当研究室の教員 or 学生)
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Masuda, Y.*, Ohki, S., Mogami, Y., Deguchi, K., Hashi, K., Goto,
A., Shimizu, T., Yamada, Y.*: Solution and solid-state 33S NMR
studies of 33S-labeled taurine. Magn. Reason. Chem. 2023,
61, 589–594.
https://doi.org/10.1002/mrc.5387
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Yamada,
K.*, Masuda, Y.*: A
sulfur-33 nuclear quadrupole resonance study of 33S2-labeled
L-cystine. Magn. Reason. Chem. 2023, 61, 296–300.
https://doi.org/10.1002/mrc.5333
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Honda,
M., Inagaki, M., Masuda, Y.*: Total synthesis of the cyclic
pentapeptides PF1171B, D, E, and avellanins A, B, C with inhibitory activity
against apolipoprotein B production. Tetrahedron
Lett., 2021, 81, 153340.
https://doi.org/10.1016/j.tetlet.2021.15334
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Yoshida,
Y., Inagaki, M., Masuda, Y.*: Solid-phase synthesis and bioactivity evaluation
of cherimolacyclopeptide E. J. Pept. Sci.
2021, e3308.
https://doi.org/10.1002/psc.3308
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Tanaka, F., Shibata, K., Monobe, Y., Akagi, K., Masuda, Y.*: Design and synthesis of beta-strand-fixed peptides inhibiting aggregation of amyloid beta-protein. Bioorg. Med. Chem. 2020, 28, 115676. https://doi.org/10.1016/j.bmc.2020.115676
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Onda,
Y., Fukushi, K., Ohsawa, K., Yoshida, M., Masuda, Y., Doi, T.*: Synthesis of a
biphenylalanine analogue of apratoxin a displaying substantially enhanced
cytotoxicity. Heterocycles, 2020, 101, 679–691. Professor Kaoru Fuji Special Issue
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Ohsawa, K, Zhao, H., Tokunaga, T., Thomas, C., Ganesan, A., Masuda, Y., Doi T.*: Stereoselective synthesis of protected L-allo-Enduracididine and L-Enduracididine via asymmetric nitroaldol reaction. Synthesis 2020, 52, 942–948.
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Kuriya, K., Nishio, M.*, Ono, N., Masuda, Y., Katsuzaki,
H., Kondo, S., Sono, J., Nakamura, M., Umekawa, H.: Isolation and
characterization of antihyperglycemic compounds from Vigna angularis
extracts. J. Food. Sci. 2019, 84, 3172–3178.
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Ohsawa, K., Sugai, M., Zhang, L., Masuda, Y., Yoshida, M.,
Doi, T.*: Total synthesis and structural revision of cyclotetrapeptide
asperterrestide A. J. Org. Chem. 2019, 84, 6765–6779.
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D’Amato, A., Della Sala, G., Izzo, I., Costabile, C.,
Masuda, Y.*, De Riccardis, F.*: Cyclic octamer peptoids: simplified
isosters of bioactive fungal cyclodepsipeptides. Molecules 2018, 23,
1779.
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Masuda, Y.*, Tanaka, R., Ganesan, A., Doi, T.*: Systematic
analysis of relationship among 3D structure, bioactivity, and membrane
permeability of PF1171F, a cyclic hexapeptide with paralyzing effects
on silkworms. J. Org. Chem. 2017, 82, 11447–11463.
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Onda, Y., Masuda, Y., Yoshida, M., Doi, T.*:
Conformation-based design and synthesis of apratoxin A mimetics
modified at the α,β-unsaturated thiazoline moiety. J. Med. Chem., 2017,
60, 6751–6765.
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Masuda, Y., Maruyama, C., Kawabata, K., Hamano, Y., Doi,
T.*: Synthesis of (2S,3R,4R)-3,4-dihydroxyarginine and its inhibitory
activity against nitric oxide synthase. Tetrahedron 2016, 72, 5602–5611.
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Masuda, Y., Aoyama, K., Yoshida, M., Kobayashi, K.,
Ohshiro, T., Tomoda, H., Doi T.*: Design, synthesis, and biological
evaluation of beauveriolide analogues bearing photoreactive amino
acids. Chem. Pharm. Bull., 2016, 64, 754–765. Special Collection of
Papers Celebrating Professor Satoshi Ōmura's 2015 Nobel Prize in
Physiology or Medicine.
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Yoshida, M., Onda, Y., Masuda, Y., Doi, T.*: Potent
oxazoline analogue of apratoxin C: synthesis, biological evaluation,
and conformational analysis. Biopolymers (Peptide Science), 2016, 106,
404–414. Special Issue: Emerging Peptide Science from Japan.
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Kawahara, T., Kagaya, N., Masuda, Y., Doi, T., Izumikawa,
M., Ohta, K., Hirao, A., Shin-Ya, K.*: Foxo3a inhibitors of microbial
origin, JBIR-141 and JBIR-142. Org. Lett. 2015, 17, 5476–5479.
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Masuda, Y., Tanaka, R., Ganesan, A.,* Doi, T.*: Structure
revision of similanamide to PF1171C by total synthesis. J. Nat. Prod.
2015, 78, 2286–2291.
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Masuda, Y., Suzuki, J., Onda, Y., Fujino, Y., Yoshida, M.,
Doi, T.*: Total synthesis and conformational analysis of apratoxin C.
J. Org. Chem. 2014, 79, 8000–8009.
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Masuda, Y., Tanaka, R., Kai, K., Ganesan, A.,* Doi, T.*:
Total synthesis and biological evaluation of PF1171A, C, F, and G,
cyclic hexapeptides with insecticidal activity. J. Org. Chem. 2014, 79,
7844−7853.
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Shen, M., Liu, Q., Trébosc, J., Lafon, O., Masuda, Y.,
Takegoshi, K., Amoureux, J. P.,* Hu, B.,* Chen, Q.: Exploring various
modulation-sideband recoupling conditions of SHA+ sequence at fast MAS.
Solid State Nucl. Magn. Reson. 2013, 55-56, 42–47.
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Sato, M., Murakami, K., Uno, M., Nakagawa, Y., Katayama,
S., Akagi, K., Masuda, Y., Takegoshi, K., Irie, K.*: Site-specific
inhibitory mechanism for amyloid-beta 42 aggregation by catechol-type
flavonoids targeting the Lys residues. J. Biol. Chem. 2013, 288,
23212–23224.
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Doi, T., Masuda, Y.*, Irie, K., Akagi, K., Monobe, Y.,
Imazawa, T., Takegoshi, K.: Solid-state NMR analysis of the beta-strand
orientation of the protofibrils of amyloid beta-protein. Biochem.
Biophys. Res. Commun. 2012, 428, 458-462.
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Hu, B.*, Trébosc, J., Lafon, O., Chen, Q., Masuda, Y.,
Takegoshi, K., Amoureux, J. P.*: Very-long-distance correlations in
proteins revealed by solid-state NMR spectroscopy. ChemPhysChem 2012,
13, 3585–3588.
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Tsuji, F., Ishihara, A., Nakagawa, A., Okada, M.,
Kitamura, S., Kanamaru, K., Masuda, Y., Murakami, K., Irie, K.,
Sakagami, Y.*: Lack of the consensus sequence necessary for tryptophan
prenylation in the ComX pheromone precursor. Biosci. Biotechnol.
Biochem. 2012, 76, 1492–1496.
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Tsuji, F., Ishihara, A., Kurata, K., Nakagawa, A., Okada,
M., Kitamura, S., Kanamaru, K., Masuda, Y., Murakami, K., Irie, K.,
Sakagami, Y.*: Geranyl modification on the tryptophan residue of
ComXRO-E-2 pheromone by a cell-free system. FEBS Lett. 2012, 586,
174–179.
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Masuda, Y.*, Fukuchi, M., Yatagawa, T., Tada, M., Takeda,
K., Irie, K., Akagi, K., Monobe, Y., Imazawa, T., Takegoshi, K.:
Solid-state NMR analysis of interaction sites of curcumin and
42-residue amyloid beta -protein fibrils. Bioorg. Med. Chem. 2011, 19,
5967–5974.
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Nakagawa, Y.*, Doi, T., Masuda, Y., Takegoshi, K.,
Igarashi, Y., Ito, Y.*: Mapping of the primary mannose-binding site of
pradimicin A. J. Am. Chem. Soc. 2011, 133, 17485–17493.
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Nakagawa, Y.*, Masuda, Y., Yamada, K., Doi, T., Takegoshi,
K., Igarashi, Y., Ito, Y.*: Solid-state NMR spectroscopic analysis of
the Ca2+-dependent mannose binding of pradimicin A. Angew. Chem. Int.
Ed. 2011, 50, 6084-6088.
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Weingarth, M., Masuda, Y., Takegoshi, K., Bodenhausen, G.,
Tekely, P.*: Sensitive 13C-13C correlation spectra of amyloid fibrils
at very high spinning frequencies and magnetic fields. J. Biomol. NMR
2011, 50, 129–136.
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Murakami, K., Horikoshi-Sakuraba, Y., Murata, N., Noda,
Y., Masuda, Y., Kinoshita, N., Hatsuta, H., Murayama, S., Shirasawa,
T., Shimizu, T.,* Irie, K.*: Monoclonal antibody against the turn of
the 42-residue amyloid beta -protein at positions 22 and 23. ACS Chem.
Neurosci. 2010, 1, 747–756.
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Kondo, T., Kajita, R., Miyazaki, A., Hokoyama, M.,
Nakamura-Miura, T., Mizuno, S., Masuda, Y., Irie, K., Tanaka, Y.,
Takada, S., Kakimoto, T., Sakagami, Y.*: Stomatal density is controlled
by a mesophyll-derived signaling molecule. Plant Cell Physiol. 2010,
51, 1–8.
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Masuda, Y., Uemura, S., Ohashi, R., Nakanishi, A.,
Takegoshi, K., Shimizu, T., Shirasawa, T., Irie, K.*: Identification of
physiological and toxic conformations in Abeta42 aggregates.
ChemBioChem 2009, 10, 287–295.
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Masuda, Y., Nakanishi, A., Ohashi, R., Takegoshi, K.,
Shimizu, T., Shirasawa, T., Irie, K.*: Verification of the
intermolecular parallel beta-sheet in E22K-Abeta42 aggregates by
solid-state NMR using rotational resonance: Implications for the
supramolecular arrangement of the toxic conformer of Abeta42. Biosci.
Biotechnol. Biochem. 2008, 72, 2170–2175.
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Masuda, Y., Uemura, S., Nakanishi, A., Ohashi, R.,
Takegoshi, K., Shimizu, T., Shirasawa, T., Irie, K.*: Verification of
the C-terminal intramolecular beta-sheet in Abeta42 aggregates using
solid-state NMR: Implications for potent neurotoxicity through the
formation of radicals. Bioorg. Med. Chem. Lett. 2008, 18, 3206–3210.
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Murakami, K., Uno, M., Masuda, Y., Shimizu, T., Shirasawa,
T., Irie, K.*: Isomerization and/or racemization at Asp23 of Abeta42 do
not increase its aggregative ability, neurotoxicity, and radical
productivity in vitro. Biochem. Biophys. Res. Commun. 2008, 366,
745–751.
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Murakami, K., Hara, H., Masuda, Y., Ohigashi, H., Irie,
K.*: Distance measurement between Tyr10 and Met35 in amyloid beta by
site-directed spin-labeling ESR spectroscopy: Implications for the
stronger neurotoxicity of Abeta42 than Abeta40. ChemBioChem 2007, 8,
2308–2314.
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Masuda, Y., Irie, K.,* Murakami, K., Ohigashi, H., Ohashi,
R., Takegoshi, K., Shimizu, T., Shirasawa, T.: Verification of the turn
at positions 22 and 23 of the beta-amyloid fibrils with Italian
mutation using solid-state NMR. Bioorg. Med. Chem. 2005, 13, 6803–6809.
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Morimoto, A., Irie, K.,* Murakami, K., Masuda, Y.,
Ohigashi, H., Nagao, M., Fukuda, H., Shimizu, T., Shirasawa, T.:
Analysis of the secondary structure of beta-amyloid (Abeta42) fibrils
by systematic proline replacement. J. Biol. Chem. 2004, 279,
52781–52788.
[総説・解説]
- 増田裕一*: 受動拡散により膜透過する中分子環状ペプチドの探索法の開発.Peptide Newsletter Japan No. 124(日本ペプチド学会), 2022年4月, pp1–3.
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Masuda, Y.*: Bioactive
3D structures of naturally occurring peptides and their application in drug
design. Biosci. Biotechnol. Biochem. 2021, 85, 24–32.
https://doi.org/10.1093/bbb/zbaa008
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増田裕一*,土井隆行*: 天然物に学ぶ環状ペプチドの三次元構造制御.CSJ Current Review 36:生体分子反応を制御する〜化学的手法による機構と反応場の解明.(化学同人) 2020, 13, 120–127.
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Doi, T.,* Masuda, Y., Yoshida, M.: Cyclodepsipeptide
Natural Products Apratoxins A and C and Their Analogs. J. Synth. Org.
Chem. Jpn. 2018, 76 (11), 1170–1175.
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増田裕一: 中分子で免疫チェックポイントを制御する.ファルマシア 2018, 54 (6), 574.
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増田裕一*,土井隆行: 生物活性環状ペプチドPF1171類とapratoxin Cの全合成と三次元構造解析.化学工業 2016, 67, 18–25.
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村上一馬,増田裕一,入江一浩*: 固体NMRおよびESRによるアミロイドβの立体構造解析と毒性ターン構造特異抗体の開発. 遺伝子医学MOOK 2012, 21, 211–216.
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Murakami, K., Masuda, Y., Shirasawa, T., Shimizu, T.,*
Irie, K.*: The turn formation at positions 22 and 23 in the 42-mer
amyloid beta peptide: The emerging role in the pathogenesis of
Alzheimer’s disease. Geriatr. Gerontol. Int. 2010, 10, S169–S179.
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増田 裕一, 入江 一浩*: ポリフェノールによるアルツハイマー病予防の可能性. FFIジャーナル 2010, 215, 53–59.
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入江 一浩,* 増田 裕一:βアミロイドの毒性コンホメーション. 化学と生物 2008, 46, 431–434.
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Irie, K.,* Murakami, K., Masuda, Y., Morimoto, A.,
Ohigashi, H., Hara, H., Ohashi, R., Takegoshi, K., Fukuda, H., Nagao,
M., Shimizu, T., Shirasawa, T.: The toxic conformation of the
42-residue amyloid beta peptide and its relevance to oxidative stress
in Alzheimer’s disease. Mini-Rev. Med. Chem. 2007, 7, 1001–1008.
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Irie, K.,* Murakami, K., Masuda, Y., Morimoto, A.,
Ohigashi, H., Ohashi, R., Takegoshi, K., Nagao, M., Shimizu, T.,
Shirasawa, T.: Structure of beta-amyloid fibrils and its relevance to
their neurotoxicity: Implications for the pathogenesis of Alzheimer’s
disease. J. Biosci. Bioeng. 2005, 99, 437–447.
[招待講演]
-
Yuichi Masuda: Elucidation of important 3D structures for
bioactivity of naturally occurring peptides. 23rd Korean Peptide and
Protein Society Symposium, Invited lecture (Daemyung Resort, Sol Beach
Yangyang, South Korea) , July 1~2, 2019.
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増田裕一: 生物活性環状ペプチドの合成と三次元構造解析. 日本薬学会東北支部 第13回化学系若手研究者セミナー (仙台) 2014年9月.
-
Masuda, Y.: Identification of Toxic Conformation in the
Aggregates of 42-residue Amyloid beta-Protein. Seminar in Unité de
Catalyse et de Chimie du Solide (UCCS) – UMR CNRS 8181, University of
Lille, (Lille, France) Novemver 2009.
-
Masuda, Y.: Identification of Toxic Conformation in the
Aggregates of 42-residue Amyloid beta-Protein. Seminar in
Département de Chimie, Ecole Normale Supérieure (Paris, France)
Novemver 2009.
[特許] (下線は当研究室の教員 or 学生)
-
増田裕一,杉山恵里: アミロイドβの凝集体の測定方法.特願2020-18764(出願日: 2020年2月6日).
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土井隆行,吉田将人,増田裕一,恩田勇一: 新規環状デプシペプチド化合物.PCT/JP2017/005777 (2017).
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Irie, K., Murakami, K., Masuda, Y., Shimizu, T.,
Shirasawa, T., Seito, T.: Antibody recognizing turn structure in
amyloid beta. 特許登録US 8,710,193; CN ZL201080046483.9 (2014).
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